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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

p70s6k-A  -  p70 S6 kinase

Xenopus laevis

 
 
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High impact information on p70s6k-A

  • Overexpression of a Xenopus MAP kinase phosphatase blocks mesoderm induction by FGF, and causes characteristic defects in mesoderm formation in intact embryos, whereas inhibition of the P13 kinase and p70 S6 kinase pathways has no effect on mesoderm induction by FGF [1].
  • Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner [2].

References

  1. Mesoderm induction in Xenopus caused by activation of MAP kinase. Umbhauer, M., Marshall, C.J., Mason, C.S., Old, R.W., Smith, J.C. Nature (1995) [Pubmed]
  2. Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner. Christie, G.R., Hajduch, E., Hundal, H.S., Proud, C.G., Taylor, P.M. J. Biol. Chem. (2002) [Pubmed]
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