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Gene Review

NFIL3  -  nuclear factor, interleukin 3 regulated

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High impact information on NFIL3

  • In the nematode, the transcription factor CES-2 predisposes neurosecretory motoneurons to death, whereas E4BP4 (NFIL3), one of its vertebrate homologs, regulates survival of pro-B lymphocytes [1].


  1. The CES-2-related transcription factor E4BP4 is an intrinsic regulator of motoneuron growth and survival. Junghans, D., Chauvet, S., Buhler, E., Dudley, K., Sykes, T., Henderson, C.E. Development (2004) [Pubmed]
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