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Gene Review: 

OCT2  -  POU-domain protein

Sus scrofa

 
 
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High impact information on OCT2

  • To resolve this issue, we made an OCT2/green fluorescent protein (GFP) fusion construct (rOCT2-GFP) and determined its localization within Xenopus laevis oocytes and renal cells using confocal microscopy [1].
  • A PstI RFLP at the porcine POU domain class 1 transcription factor 1 (POU1F1) gene [2].
  • The 478 amino acid-long reading frame in pig OCT2 is 97% identical to human OCT2A, indicating strong conservation of function for this immunoglobulin regulatory protein [3].
 

Biological context of OCT2

 

Analytical, diagnostic and therapeutic context of OCT2

References

  1. Basolateral localization of organic cation transporter 2 in intact renal proximal tubules. Sweet, D.H., Miller, D.S., Pritchard, J.B. Am. J. Physiol. Renal Physiol. (2000) [Pubmed]
  2. A PstI RFLP at the porcine POU domain class 1 transcription factor 1 (POU1F1) gene. Nielsen, V.H., Larsen, N.J. Anim. Genet. (1997) [Pubmed]
  3. Cloning, sequencing and restriction fragment length polymorphism analysis of a porcine cDNA for OCT2. Tuggle, C.K., Helm, J., Rothschild, M.F. Anim. Genet. (1994) [Pubmed]
  4. Rapid communication: cloning and sequence analysis of the swine Oct-2 POU-domain genomic region. Tuggle, C.K. J. Anim. Sci. (1993) [Pubmed]
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