Gene Review:
CEBPB - CCAAT/enhancer binding protein (C/EBP), beta
Sus scrofa
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High impact information on CEBPB
- CCAAT/enhancer binding proteins alpha and beta (CEBPA/ CEBPB) were evaluated in the porcine ovary during the estrous cycle [1].
- The 34-kDa form of CEBPB was decreased by the protein kinase A inhibitor H89 at 4 h (with FSH treatment), and by both protein kinase A and phosphatidylinositol 3-kinase inhibitors at 24 h of treatment [1].
- These data implicate protein kinase A as the major regulator of CEBPB isoform distribution and CEBP-mediated transactivation in granulosa cells [1].
Anatomical context of CEBPB
- CEBPB mRNA was present in antral follicles and was significantly increased in healthy corpora lutea (CL), whereas CEBPA mRNA was constitutively expressed in these structures [1].
References
- Expression of CCAAT/enhancer binding proteins alpha and beta in the porcine ovary and regulation in primary cultures of granulosa cells. Gillio-Meina, C., Hui, Y.Y., LaVoie, H.A. Biol. Reprod. (2005) [Pubmed]
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