Gene Review:
JUP - junction plakoglobin
Sus scrofa
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High impact information on JUP
- Western blot analysis indicated that protein levels of VE-cadherin, alpha-catenin, and plakoglobin decreased, whereas beta-catenin levels increased after 8.5 hours of shear stress [1].
- As cell shape change reached completion (24 to 48 hours), all protein levels were upregulated except for plakoglobin, which remained below control levels [1].
References
- Transient and steady-state effects of shear stress on endothelial cell adherens junctions. Noria, S., Cowan, D.B., Gotlieb, A.I., Langille, B.L. Circ. Res. (1999) [Pubmed]
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