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Gene Review

bix1.1  -  Brachyury-inducible homeobox 1, gene 1

Xenopus laevis

Synonyms: bix1, tBix
 
 
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High impact information on Bix1

  • Rather, Bix3 lacks a C-terminal motif, which, in Bix1, acts in cis to inhibit apoptosis [1].
  • Mis-expression of low levels of Bix1 causes formation of ventral mesoderm, while high levels induce endodermal differentiation [2].
  • Bix1, a direct target of Xenopus T-box genes, causes formation of ventral mesoderm and endoderm [2].

References

  1. Regulation of apoptosis in theXenopus embryo by Bix3. Trindade, M., Messenger, N., Papin, C., Grimmer, D., Fairclough, L., Tada, M., Smith, J.C. Development (2003) [Pubmed]
  2. Bix1, a direct target of Xenopus T-box genes, causes formation of ventral mesoderm and endoderm. Tada, M., Casey, E.S., Fairclough, L., Smith, J.C. Development (1998) [Pubmed]
 
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