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Gene Review

zic5  -  zic family member 5 (odd-paired homolog,...

Danio rerio

Synonyms: SO:0000704
 
 
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High impact information on zic5

  • As a step towards better understanding this mechanism, we have identified two new Wnt targets, the closely linked zic2a and zic5 genes [1].
  • We report here the isolation of two new members of this gene family in zebrafish, zic2.2 and zic5, isolated during random screening for tissue-specific genes [2].
 

Anatomical context of zic5

  • Using a combination of in vivo assays, we show that zic2a and zic5 transcription is activated by Tcf/Lef transcription factors in the dorsal midbrain [1].
 

Other interactions of zic5

References

  1. The zebrafish zic2a-zic5 gene pair acts downstream of canonical Wnt signaling to control cell proliferation in the developing tectum. Nyholm, M.K., Wu, S.F., Dorsky, R.I., Grinblat, Y. Development (2007) [Pubmed]
  2. Sequence relationships and expression patterns of zebrafish zic2 and zic5 genes. Toyama, R., Gomez, D.M., Mana, M.D., Dawid, I.B. Gene Expr. Patterns (2004) [Pubmed]
 
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