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Gene Review

MMP14  -  matrix metallopeptidase 14 (membrane...

Canis lupus familiaris

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High impact information on MMP14

  • Recently, we demonstrated that the expression of MMP-2, MMP-9 and MMP-14 was upregulated in the renal cortex of dogs with a spontaneous form of XLAS [1].
  • Canine MMP-14 mRNA was detected in all three cell lines [2].


  1. Dysregulation of renal MMP-3 and MMP-7 in canine X-linked Alport syndrome. Rao, V.H., Lees, G.E., Kashtan, C.E., Delimont, D.C., Singh, R., Meehan, D.T., Bhattacharya, G., Berridge, B.R., Cosgrove, D. Pediatr. Nephrol. (2005) [Pubmed]
  2. Immunological and inflammatory characterisation of three canine cell lines: K1, K6 and DH82. Barnes, A., Bee, A., Bell, S., Gilmore, W., Mee, A., Morris, R., Carter, S.D. Vet. Immunol. Immunopathol. (2000) [Pubmed]
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