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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

pyd3  -  CG3027 gene product from transcript CG3027-RA

Drosophila melanogaster

Synonyms: CG3027, Dmel\CG3027, betaAS, betaASase
 
 
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High impact information on pyd3

  • Similarly, su(r) mutants are hypersensitive to dietary 5-fluorouracil, CRMP mutants are less sensitive, and pyd3 mutants exhibit wild-type sensitivity [1].
  • The truncated wing phenotype of rudimentary mutants is suppressed completely by su(r) mutations and partially by CRMP mutations; however, no suppression is exhibited by pyd3 mutations [1].
  • A Saccharomyces kluyveri pyd3 mutant that is unable to grow on N-carbamyl-beta-alanine as the sole nitrogen source and exhibits diminished beta-alanine synthase activity was used to clone analogous genes from different eukaryotes [2].

References

  1. Analysis of pyrimidine catabolism in Drosophila melanogaster using epistatic interactions with mutations of pyrimidine biosynthesis and beta-alanine metabolism. Rawls, J.M. Genetics (2006) [Pubmed]
  2. Eukaryotic beta-alanine synthases are functionally related but have a high degree of structural diversity. Gojković, Z., Sandrini, M.P., Piskur, J. Genetics (2001) [Pubmed]
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