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Gene Review

Task7  -  TWIK-related acid-sensitive K[+] channel 7

Drosophila melanogaster

Synonyms: CG9361, Dmel\CG9361, K2P-TASK7, dTASK-7
 
 
 
 
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High impact information on Task7

  • Following cotransfection of dTASK-6 and wildtype dTASK-7 (or when engineered as concatemers), K(+) currents were observed that were smaller in amplitude, harbored slower activation kinetics and were considerably less inhibited by local anesthetics as compared with dTASK-6 [1].
 

Other interactions of Task7

  • Nonfunctional wildtype dTASK-7 channels appeared to form heteromeric assemblies with dTASK-6 [1].

References

  1. Novel Drosophila two-pore domain K channels: rescue of channel function by heteromeric assembly. D??ring, F., Scholz, H., K??hnlein, R.P., Karschin, A., Wischmeyer, E. Eur. J. Neurosci. (2006) [Pubmed]
 
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