Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

PP2A-B' - CG7913 gene product from transcript CG7913-RK

Drosophila melanogaster

Synonyms: B', B'/PR61, B56-1, BcDNA:GM05554, CG 7913, ...

Berry, M. et al., Li, X. et al.

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High impact information on PP2A-B'

A DROSOPHILA: homologue of the regulatory subunit (B'/PR61) of serine-threonine protein phosphatase 2A (dPP2A,B') specifically interacted with the SCR homeodomain [1].
B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster [2].
Global knockdown of PP2A activity or specific loss of redundant B56 regulatory subunits caused cell death with the morphological and biochemical changes characteristic of apoptosis in cultured S2 cells [2].

References

Phosphorylation status of the SCR homeodomain determines its functional activity: essential role for protein phosphatase 2A,B'. Berry, M., Gehring, W. EMBO J. (2000) [Pubmed]
B56-associated protein phosphatase 2A is required for survival and protects from apoptosis in Drosophila melanogaster. Li, X., Scuderi, A., Letsou, A., Virshup, D.M. Mol. Cell. Biol. (2002) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

ATB' DELTA	Arabidopsis thaliana
PPP2R5D	Bos taurus
pptr-2	Caenorhabditis elegans
PPP2R5D	Canis lupus familiaris
ppp2r5d	Danio rerio
PPP2R5D	Gallus gallus
PPP2R5D	Homo sapiens
PPP2R5D	Macaca mulatta
Ppp2r5d	Mus musculus
PPP2R5D	Pan troglodytes
Ppp2r5d	Rattus norvegicus
par2	Schizosaccharomyces pombe 972h-

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