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Gene Review

Hrb98DE  -  Heterogeneous nuclear ribonucleoprotein at...

Drosophila melanogaster

Synonyms: CG9983, Dmel\CG9983, E7Delta6, HDP(P9), HRB98DE, ...
 
 
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High impact information on Hrb98DE

  • We have previously identified two genes in Drosophila melanogaster, Hrb98DE and Hrb87F (i.e., genes at 98DE and 87F encoding putative hnRNA binding proteins), which encode five protein species homologous to the mammalian A-B hnRNP proteins [1].
  • The Hrb98DE locus is transcribed throughout development, with the highest transcript levels found in ovaries, early embryos, and pupae [2].
  • We have been studying two Drosophila RNP motif proteins, Hrb98DE and Hrb87F, which are hnRNA-binding proteins [3].
  • We report here that the Drosophila genome contains a family of genes related to the Hrb98DE gene [4].
 

Other interactions of Hrb98DE

  • One member of the family, Hrb87F, is very homologous to Hrb98DE in both sequence and structure [4].

References

  1. Heterogeneous nuclear ribonucleoprotein complexes and proteins in Drosophila melanogaster. Raychaudhuri, G., Haynes, S.R., Beyer, A.L. Mol. Cell. Biol. (1992) [Pubmed]
  2. The Drosophila Hrb98DE locus encodes four protein isoforms homologous to the A1 protein of mammalian heterogeneous nuclear ribonucleoprotein complexes. Haynes, S.R., Raychaudhuri, G., Beyer, A.L. Mol. Cell. Biol. (1990) [Pubmed]
  3. The Rb97D gene encodes a potential RNA-binding protein required for spermatogenesis in Drosophila. Karsch-Mizrachi, I., Haynes, S.R. Nucleic Acids Res. (1993) [Pubmed]
  4. The Drosophila Hrb87F gene encodes a new member of the A and B hnRNP protein group. Haynes, S.R., Johnson, D., Raychaudhuri, G., Beyer, A.L. Nucleic Acids Res. (1991) [Pubmed]
 
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