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Gene Review

bip2  -  CG2009 gene product from transcript CG2009-RA

Drosophila melanogaster

Synonyms: BIP2, Bip2, CG2009, DmTAF3, Dmel\CG2009, ...
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High impact information on bip2

  • TFIID has been extensively characterized for yeast, Drosophila, and humans, demonstrating a high degree of conservation of both the amino acid sequences of the constituent TAF(II)s and overall molecular organization [1].
  • BIP2 is a novel Drosophila TATA-box Protein Associated Factor (TAF(II)), also named dTAF(II)155 [2].

Analytical, diagnostic and therapeutic context of bip2

  • We have cloned a novel mouse protein, TAF(II)140, containing an HFD and a plant homeodomain (PHD) finger, which we demonstrated by immunoprecipitation to be a mammalian TFIID component [1].


  1. The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD finger. Gangloff, Y.G., Pointud, J.C., Thuault, S., Carré, L., Romier, C., Muratoglu, S., Brand, M., Tora, L., Couderc, J.L., Davidson, I. Mol. Cell. Biol. (2001) [Pubmed]
  2. The BTB/POZ domain of the regulatory proteins Bric à brac 1 (BAB1) and Bric à brac 2 (BAB2) interacts with the novel Drosophila TAF(II) factor BIP2/dTAF(II)155. Pointud, J.C., Larsson, J., Dastugue, B., Couderc, J.L. Dev. Biol. (2001) [Pubmed]
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