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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Cpsf160  -  Cleavage and polyadenylation specificity...

Drosophila melanogaster

Synonyms: CG10110, CPSF, CPSF 160 kDa subunit, CPSF-160, CPSF160, ...
 
 
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High impact information on cpsf

  • An essential component of the mammalian pre-mRNA 3'-end processing machinery is a multimeric protein complex known as cleavage and polyadenylation specificity factor (CPSF) [1].
  • Mutations in the cpsf gene did not alter the phenotype of homozygous su(f) mutations, suggesting that, for most genes, processing of 3' termini is not sensitive to small changes in cpsf and su(f) dosage [2].
 

Biological context of cpsf

  • Characterization of a Drosophila homologue of the 160-kDa subunit of the cleavage and polyadenylation specificity factor CPSF [2].

References

  1. Drosophila clipper/CPSF 30K is a post-transcriptionally regulated nuclear protein that binds RNA containing GC clusters. Bai, C., Tolias, P.P. Nucleic Acids Res. (1998) [Pubmed]
  2. Characterization of a Drosophila homologue of the 160-kDa subunit of the cleavage and polyadenylation specificity factor CPSF. Salinas, C.A., Sinclair, D.A., O'Hare, K., Brock, H.W. Mol. Gen. Genet. (1998) [Pubmed]
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