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Gene Review:

ctm1 - tropomyosin

Ciona intestinalis

Crowther, R.J. et al., Meedel, T.H. et al.

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High impact information on Ctm1

Differentiation of tropomyosin-containing myofibrils in cleavage-arrested ascidian zygotes expressing acetylcholinesterase [1].
Striated muscle-type tropomyosin in a chordate smooth muscle, ascidian body-wall muscle [2].
We also found that an apparently identical Tm isoform, derived from the same gene, is expressed at high levels in Ciona heart, a striated muscle [2].

Anatomical context of Ctm1

As demonstrated by immunogold labelling, a polyclonal antibody to tropomyosin from Ciona adult body wall reacted differentially with the presumed ultrastructural muscle elements in cleavage-arrested zygotes [1].

References

Differentiation of tropomyosin-containing myofibrils in cleavage-arrested ascidian zygotes expressing acetylcholinesterase. Crowther, R.J., Meedel, T.H., Whittaker, J.R. Development (1990) [Pubmed]
Striated muscle-type tropomyosin in a chordate smooth muscle, ascidian body-wall muscle. Meedel, T.H., Hastings, K.E. J. Biol. Chem. (1993) [Pubmed]

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