Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

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Gene Review:

san - separation anxiety

Drosophila melanogaster

Synonyms: CG12352, DmAAF34715, Dmel\CG12352, Protein separation anxiety, atado, ...

Williams, B.C. et al.

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Psychiatry related information on san

However, many aspects of the mechanisms that establish and maintain cohesion during mitosis remain unclear.RESULTS: We found that mutations in two evolutionarily conserved Drosophila genes, san (separation anxiety) and deco (Drosophila eco1), disrupt centromeric sister chromatid cohesion very early in division [1].

High impact information on san

Two putative acetyltransferases, san and deco, are required for establishing sister chromatid cohesion in Drosophila [1].

Associations of san with chemical compounds

Both san and deco are predicted to encode acetyltransferases, which transfer acetyl groups either to internal lysine residues or to the N terminus of other proteins [1].

References

Two putative acetyltransferases, san and deco, are required for establishing sister chromatid cohesion in Drosophila. Williams, B.C., Garrett-Engele, C.M., Li, Z., Williams, E.V., Rosenman, E.D., Goldberg, M.L. Curr. Biol. (2003) [Pubmed]

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AgaP_AGAP002568	Anopheles gambiae str. PEST
AT5G11340	Arabidopsis thaliana
F40F4.7	Caenorhabditis elegans
LOC102553099	Rattus norvegicus

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