The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

OPA2  -  optic atrophy 2 (obscure)

Homo sapiens

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of OPA2


High impact information on OPA2

  • Twenty-four new localizations have been established, including five in previously reported conditions (FG, Carpenter, Arts, OPA2, and OFD1) [2].
  • A family with X-linked optic atrophy linked to the OPA2 locus Xp11.4-Xp11.2 [3].
  • Preliminary linkage analysis (LOD score = 1.8) revealed that the disease gene localized to the OPA2 locus on Xp11.4-Xp11 [3].
  • Linkage analysis excluded OPA1 and OPA2 [4].


  1. Molecular genetic basis of primary inherited optic neuropathies. Votruba, M. Eye (London, England) (2004) [Pubmed]
  2. XLMR genes: update 1998. Lubs, H., Chiurazzi, P., Arena, J., Schwartz, C., Tranebjaerg, L., Neri, G. Am. J. Med. Genet. (1999) [Pubmed]
  3. A family with X-linked optic atrophy linked to the OPA2 locus Xp11.4-Xp11.2. Katz, B.J., Zhao, Y., Warner, J.E., Tong, Z., Yang, Z., Zhang, K. Am. J. Med. Genet. A (2006) [Pubmed]
  4. Progressive autosomal dominant optic atrophy and sensorineural hearing loss in a Turkish family. Ozden, S., Düzcan, F., Wollnik, B., Cetin, O.G., Sahiner, T., Bayramoğlu, I., Yüksel-Apak, M., Bağci, H. Ophthalmic Genet. (2002) [Pubmed]
WikiGenes - Universities