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Gene Review

TRIM5  -  tripartite motif containing 5

Pan troglodytes

 
 
 
 
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High impact information on TRIM5

  • We found several nonsynonymous SNPs at the human TRIM5 locus, but only one of these (H43Y) was found to have a significant functional consequence [1].

References

  1. High-frequency persistence of an impaired allele of the retroviral defense gene TRIM5alpha in humans. Sawyer, S.L., Wu, L.I., Akey, J.M., Emerman, M., Malik, H.S. Curr. Biol. (2006) [Pubmed]
 
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