The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

Editor

Share

Personal info

View

Links

  • Homologues
  • NCBI Gene
  • NCBI SNP
  • iHOP resource
  • SNPedia

Table of contents

About

Terms

 

Gene Review: 

C5  -  complement component 5

Bos taurus

 
 
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.
 

High impact information on LOC512045

  • An internal thioester in the alpha-chain of C3 (present in C4 but not in C5) is cleaved during complement activation [1].
 

Analytical, diagnostic and therapeutic context of LOC512045

  • The chemotactically active agent has been identified as the low m.w. C5 cleavage product (C5a) on the basis of heat stability, gel filtration characteristics, and specific inhibition by anti-serum to C5 [2].

References

  1. The structure of bovine complement component 3 reveals the basis for thioester function. Fredslund, F., Jenner, L., Husted, L.B., Nyborg, J., Andersen, G.R., Sottrup-Jensen, L. J. Mol. Biol. (2006) [Pubmed]
  2. Generation of a neutrophil chemotactic agent by spermatozoa: role of complement and regulation by seminal plasma factors. Clark, R.A., Klebanoff, S.J. J. Immunol. (1976) [Pubmed]
Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenesOpen Access LicencePrivacy PolicyTerms of Useapsburg
 
WikiGenes - Universities