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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

RIPPLY3  -  ripply transcriptional repressor 3

Homo sapiens

Synonyms: DSCR6, Down syndrome critical region protein 6, Protein ripply3
 
 
 
 
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Disease relevance of DSCR6

  • Both DSCR5 and DSCR6 genes are candidates for the pathogenesis of Down syndrome, although the function of these genes remains to be elucidated [1].
 

High impact information on DSCR6

  • The DSCR5 gene is expressed in various human tissues examined, whereas the DSCR6 gene is expressed only in limited tissues at low level [1].
  • DSCR5 and DSCR6 genes consist of 6 and 5 exons, respectively [1].
 

Biological context of DSCR6

References

  1. Isolation of two novel genes, DSCR5 and DSCR6, from Down syndrome critical region on human chromosome 21q22.2. Shibuya, K., Kudoh, J., Minoshima, S., Kawasaki, K., Asakawa, S., Shimizu, N. Biochem. Biophys. Res. Commun. (2000) [Pubmed]
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