Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)

Editor

Personal info

View

About

Terms

Javascript disabled

Please enable Javascript support in your browser to use this application.

Instructions on how to enable JavaScript on different browsers can be found here: http://www.google.com/support/bin/answer.py?answer=23852.

[edit this page]

Gene Review:

Pdlim1 - PDZ and LIM domain 1 (elfin)

Mus musculus

Synonyms: C-terminal LIM domain protein 1, CLP36, Clim1, Elfin, LIM domain protein CLP-36, ...

Kotaka, M. et al.

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

High impact information on Pdlim1

We have previously shown that Elfin is most abundantly expressed in the heart and it colocalizes with alpha-actinin 2 at the Z-disks of the myocardium [1].
Taken together, our experimental results suggest that Elfin may play an important role in myofibrillogenesis and heart development [1].
In this report, Elfin was shown to localize at the actin stress fibers of myoblasts, as revealed by green fluorescent protein (GFP) tagging [1].

Analytical, diagnostic and therapeutic context of Pdlim1

In situ hybridization and immunostaining showed that Elfin expression begins at an early stage in mouse development and is present throughout the developing heart [1].

References

Elfin is expressed during early heart development. Kotaka, M., Lau, Y.M., Cheung, K.K., Lee, S.M., Li, H.Y., Chan, W.Y., Fung, K.P., Lee, C.Y., Waye, M.M., Tsui, S.K. J. Cell. Biochem. (2001) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

PDLIM1	Bos taurus
PDLIM1	Canis lupus familiaris
pdlim1	Danio rerio
PDLIM1	Gallus gallus
PDLIM1	Homo sapiens
PDLIM1	Macaca mulatta
PDLIM1	Pan troglodytes
Pdlim1	Rattus norvegicus
pdlim1	Xenopus (Silurana) tropicalis

The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.