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Gene Review

AGPAT5  -  1-acylglycerol-3-phosphate O...

Homo sapiens

Synonyms: 1-AGP acyltransferase 5, 1-AGPAT 5, 1-acyl-sn-glycerol-3-phosphate acyltransferase epsilon, 1AGPAT5, FLJ11210, ...
 
 
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High impact information on AGPAT5

  • Genomic analysis identifies highly conserved GATA-3 binding sites bound in vivo by GATA-3 in the first intron of the lipid acyltransferase gene AGPAT5 [1].
  • AGPAT8 is most closely related to AGPAT5, and its cDNA is expressed most in the heart, while AGPAT5 is expressed more in the prostate and testis [2].

References

  1. Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3. de Guzman Strong, C., Wertz, P.W., Wang, C., Yang, F., Meltzer, P.S., Andl, T., Millar, S.E., Ho, I.C., Pai, S.Y., Segre, J.A. J. Cell Biol. (2006) [Pubmed]
  2. Functional characterization of human 1-acylglycerol-3-phosphate acyltransferase isoform 8: Cloning, tissue distribution, gene structure, and enzymatic activity. Agarwal, A.K., Barnes, R.I., Garg, A. Arch. Biochem. Biophys. (2006) [Pubmed]
 
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