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Gene Review

PPP3CC  -  protein phosphatase 3, catalytic subunit,...

Homo sapiens

Synonyms: CALNA3, CAM-PRP catalytic subunit, CNA3, Calcineurin, testis-specific catalytic subunit, Calmodulin-dependent calcineurin A subunit gamma isoform, ...
 
 
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High impact information on PPP3CC

  • Transmission disequilibrium studies in a large sample of affected families detected association of the PPP3CC gene, which encodes the calcineurin gamma catalytic subunit, with disease [1].
  • Evidence for association of schizophrenia with genetic variation in the 8p21.3 gene, PPP3CC, encoding the calcineurin gamma subunit [1].
  • A haplotype of the PPP3CC gene, which encodes the gamma isoform of the catalytic subunit (CaN A), has been associated with schizophrenia [2].
  • Consistent with these findings, human genetics studies in a large sample of affected families detected a significant association of the PPP3CC gene, which encodes the CN gamma catalytic subunit with schizophrenia [3].

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