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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 
MeSH Review

Variation (Genetics)

 
 
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Disease relevance of Variation (Genetics)

 

Psychiatry related information on Variation (Genetics)

 

High impact information on Variation (Genetics)

 

Chemical compound and disease context of Variation (Genetics)

 

Biological context of Variation (Genetics)

 

Anatomical context of Variation (Genetics)

  • These data suggest a continuum of resistance conferred by NK cell inhibition to susceptibility involving NK cell activation in the development of cervical neoplasia and underscore the pervasive influence of KIR/HLA genetic variation in human disease pathogenesis [25].
  • Substantially less genetic variation has been recognized in studies of the proteins of nucleated cells by the technique of two-dimensional polyacrylamide gel electrophoresis than has been encountered in studies of serum transport proteins and erythrocyte enzymes with one-dimensional electrophoresis [26].
  • We have investigated the extent of genetic variation and the number of germ-line heavy-chain-variable (VH) genes to obtain information on the organization and repertoire of the VH genes [27].
  • Here, we demonstrate that genetic variation in the rate of thymic involution correlates with genetic variation in the responsiveness of hematopoietic stem and progenitor cells to TGF-beta2 [28].
  • These findings support the hypothesis of a germinal center B cell-derived origin of NLPHL, indicate a significant role of BCL6 in the pathogenesis of NLPHL, and provide further evidence of the genetic diversity underlying the pathogenesis of NLPHL and cHL [29].
 

Associations of Variation (Genetics) with chemical compounds

 

Gene context of Variation (Genetics)

 

Analytical, diagnostic and therapeutic context of Variation (Genetics)

References

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  16. Polymorphisms and haplotypes in folate-metabolizing genes and risk of non-Hodgkin lymphoma. Skibola, C.F., Forrest, M.S., Coppedé, F., Agana, L., Hubbard, A., Smith, M.T., Bracci, P.M., Holly, E.A. Blood (2004) [Pubmed]
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