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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

BMP2K  -  BMP2 inducible kinase

Homo sapiens

Synonyms: BIKE, BIKe, BMP-2-inducible protein kinase, DKFZp434K0614, HRIHFB2017
 
 
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High impact information on BMP2K

  • The BIKe nuclear localization signal is able to direct green fluorescent protein to the nucleus in transfected COS-7 cells [1].
  • Ten competitive male cyclists completed a Wingate Bike Test (WIN), a 30-min self-paced cycling performance bout (END), and a constant load, supramaximal cycling spring (SPN) to fatigue following 5 d of oral supplementation (5,000 mg.day-1) with inosine and placebo [2].
  • Changes in BMP2K and PRMT3 were confirmed at mRNA and protein levels, in vitro and in vivo [3].

References

  1. Cloning and characterization of a novel protein kinase that impairs osteoblast differentiation in vitro. Kearns, A.E., Donohue, M.M., Sanyal, B., Demay, M.B. J. Biol. Chem. (2001) [Pubmed]
  2. Effect of inosine supplementation on aerobic and anaerobic cycling performance. Starling, R.D., Trappe, T.A., Short, K.R., Sheffield-Moore, M., Jozsi, A.C., Fink, W.J., Costill, D.L. Medicine and science in sports and exercise. (1996) [Pubmed]
  3. Effects of ADMA upon gene expression: an insight into the pathophysiological significance of raised plasma ADMA. Smith, C.L., Anthony, S., Hubank, M., Leiper, J.M., Vallance, P. PLoS Med. (2005) [Pubmed]
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