Chemical Compound Review:
Ara-HX 9-[3,4-dihydroxy-5- (hydroxymethyl)oxolan-2...
Synonyms:
Inosine-8-14C, ACMC-209m62, H1383_SIGMA, I7637_SIGMA, NSC-20262, ...
- Inosine pranobex for preventing AIDS in patients with HIV infection. Forthal, D.N. N. Engl. J. Med. (1991)
- Impairment of cardiac function and energetics in experimental renal failure. Raine, A.E., Seymour, A.M., Roberts, A.F., Radda, G.K., Ledingham, J.G. J. Clin. Invest. (1993)
- Mechanisms whereby exogenous adenine nucleotides improve rabbit renal proximal function during and after anoxia. Mandel, L.J., Takano, T., Soltoff, S.P., Murdaugh, S. J. Clin. Invest. (1988)
- Excess purine degradation in exercising muscles of patients with glycogen storage disease types V and VII. Mineo, I., Kono, N., Shimizu, T., Hara, N., Yamada, Y., Sumi, S., Nonaka, K., Tarui, S. J. Clin. Invest. (1985)
- Treatment of first-attack genital herpes--acyclovir versus inosine pranobex. Mindel, A., Kinghorn, G., Allason-Jones, E., Woolley, P., Barton, I., Faherty, A., Jeavons, M., Williams, P., Patou, G. Lancet (1987)
- Electroshock seizures in mice: effect on brain adenosine and its metabolites. Lewin, E., Bleck, V. Epilepsia (1981)
- Central effects of nicotinamide and inosine which are not mediated through benzodiazepine receptors. Bold, J.M., Gardner, C.R., Walker, R.J. Br. J. Pharmacol. (1985)
- An expanded genetic linkage map of Prunus based on an interspecific cross between almond and peach. Bliss, F.A., Arulsekar, S., Foolad, M.R., Becerra, V., Gillen, A.M., Warburton, M.L., Dandekar, A.M., Kocsisne, G.M., Mydin, K.K. Genome (2002)
- Inosine reduces ischemic brain injury in rats. Shen, H., Chen, G.J., Harvey, B.K., Bickford, P.C., Wang, Y. Stroke (2005)
- A novel selective nucleoside phosphorylating enzyme from Morganella morganii. Asano, Y., Mihara, Y., Yamada, H. J. Biosci. Bioeng. (1999)
- The fate of dsRNA in the nucleus: a p54(nrb)-containing complex mediates the nuclear retention of promiscuously A-to-I edited RNAs. Zhang, Z., Carmichael, G.G. Cell (2001)
- The efficacy of inosine pranobex in preventing the acquired immunodeficiency syndrome in patients with human immunodeficiency virus infection. The Scandinavian Isoprinosine Study Group. Pedersen, C., Sandström, E., Petersen, C.S., Norkrans, G., Gerstoft, J., Karlsson, A., Christensen, K.C., Håkansson, C., Pehrson, P.O., Nielsen, J.O. N. Engl. J. Med. (1990)
- An unwinding activity that covalently modifies its double-stranded RNA substrate. Bass, B.L., Weintraub, H. Cell (1988)
- In-vitro inhibition of LAV/HTLV-III infected lymphocytes by dithiocarb and inosine pranobex. Pompidou, A., Zagury, D., Gallo, R.C., Sun, D., Thornton, A., Sarin, P.S. Lancet (1985)
- Myocardial lactate and adenosine metabolite production as indicators of exercise-induced myocardial ischemia in the dog. Vrobel, T.R., Jorgensen, C.R., Bache, R.J. Circulation (1982)
- Molecular transformation of tumor adenylosuccinate synthetase and characteristics of its converting factor. Matsuda, Y., Shiraki, H., Nakagawa, H. Cancer Res. (1982)
- The reversal of methotrexate cytotoxicity to mouse bone marrow cells by leucovorin and nucleosides. Pinedo, H.M., Zaharko, D.S., Bull, J.M., Chabner, B.A. Cancer Res. (1976)
- Future therapy of hepatitis C. McHutchison, J.G., Patel, K. Hepatology (2002)
- Editing of glutamate receptor subunit B pre-mRNA in vitro by site-specific deamination of adenosine. Yang, J.H., Sklar, P., Axel, R., Maniatis, T. Nature (1995)
- Structural basis for the activation of glycogen phosphorylase b by adenosine monophosphate. Sprang, S.R., Withers, S.G., Goldsmith, E.J., Fletterick, R.J., Madsen, N.B. Science (1991)
- Erythrocyte membrane proteins in hereditary glucosephosphate isomerase deficiency. Coetzer, T., Zail, S.S. J. Clin. Invest. (1979)
- Adenosine and inosine increase cutaneous vasopermeability by activating A(3) receptors on mast cells. Tilley, S.L., Wagoner, V.A., Salvatore, C.A., Jacobson, M.A., Koller, B.H. J. Clin. Invest. (2000)
- Abnormal purine metabolism and purine overproduction in a patient deficient in purine nucleoside phosphorylase. Cohen, A., Doyle, D., Martin, D.W., Ammann, A.J. N. Engl. J. Med. (1976)
- An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes. Kimelman, D., Kirschner, M.W. Cell (1989)
- Probing the function of the eucaryotic 5' cap structure by using a monoclonal antibody directed against cap-binding proteins. Sonenberg, N., Guertin, D., Cleveland, D., Trachsel, H. Cell (1981)
- Adenosine: a physiological modulator of superoxide anion generation by human neutrophils. Cronstein, B.N., Kramer, S.B., Weissmann, G., Hirschhorn, R. J. Exp. Med. (1983)
- Oxypurine cycle in human erythrocytes regulated by pH, inorganic phosphate, and oxygen. Berman, P.A., Black, D.A., Human, L., Harley, E.H. J. Clin. Invest. (1988)
- Proposed explanation for S-adenosylhomocysteine hydrolase deficiency in purine nucleoside phosphorylase and hypoxanthine-guanine phosphoribosyltransferase-deficient patients. Hershfield, M.S. J. Clin. Invest. (1981)
- The purine nucleotide cycle. A pathway for ammonia production in the rat kidney. Bogusky, R.T., Lowenstein, L.M., Lowenstein, J.M. J. Clin. Invest. (1976)
- Sodium-dependent nucleoside transport in rabbit intestinal epithelium. Roden, M., Paterson, A.R., Turnheim, K. Gastroenterology (1991)
- Activation of anti-hepatitis C virus responses via Toll-like receptor 7. Lee, J., Wu, C.C., Lee, K.J., Chuang, T.H., Katakura, K., Liu, Y.T., Chan, M., Tawatao, R., Chung, M., Shen, C., Cottam, H.B., Lai, M.M., Raz, E., Carson, D.A. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Molecular cloning and expression of human leukotriene-C4 synthase. Welsch, D.J., Creely, D.P., Hauser, S.D., Mathis, K.J., Krivi, G.G., Isakson, P.C. Proc. Natl. Acad. Sci. U.S.A. (1994)
- Mutations in the inosine monophosphate dehydrogenase 1 gene (IMPDH1) cause the RP10 form of autosomal dominant retinitis pigmentosa. Bowne, S.J., Sullivan, L.S., Blanton, S.H., Cepko, C.L., Blackshaw, S., Birch, D.G., Hughbanks-Wheaton, D., Heckenlively, J.R., Daiger, S.P. Hum. Mol. Genet. (2002)
- Use of the integrated steady state rate equation to investigate product inhibition of human red cell adenosine deaminase and its relevance to immune dysfunction. Osborne, W.R., Chen, S.H., Scott, C.R. J. Biol. Chem. (1978)
- Adenosine to inosine editing by ADAR2 requires formation of a ternary complex on the GluR-B R/G site. Jaikaran, D.C., Collins, C.H., MacMillan, A.M. J. Biol. Chem. (2002)
- Inosine-containing primers for mRNA differential display. Rohrwild, M., Alpan, R.S., Liang, P., Pardee, A.B. Trends Genet. (1995)
- Efficacy of recombinant-derived human superoxide dismutase on porcine left ventricular contractility after normothermic global myocardial ischemia and hypothermic cardioplegic arrest. Dworkin, G.H., Abd-Elfattah, A.S., Yeh, T., Wechsler, A.S. Circulation (1990)
- A double-stranded RNA unwinding activity introduces structural alterations by means of adenosine to inosine conversions in mammalian cells and Xenopus eggs. Wagner, R.W., Smith, J.E., Cooperman, B.S., Nishikura, K. Proc. Natl. Acad. Sci. U.S.A. (1989)
- Protection of the stunned myocardium. Selective nucleoside transport blocker administered after 20 minutes of ischemia augments recovery of ventricular function. Abd-Elfattah, A.S., Ding, M., Dyke, C.M., Wechsler, A.S. Circulation (1993)