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Gene Review:

KCMF1 - potassium channel modulatory factor 1

Homo sapiens

Synonyms: DEBT91, DKFZP434L1021, E3 ubiquitin-protein ligase KCMF1, FGF-induced in gastric cancer, FIGC, ...

Jang, J.H., Kreppel, M. et al.

Jang,

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Disease relevance of KCMF1

FIGC, a novel FGF-induced ubiquitin-protein ligase in gastric cancers [1].
Suppression of KCMF1 by constitutive high CD99 expression is involved in the migratory ability of Ewing's sarcoma cells [2].

High impact information on KCMF1

Our data indicate that FIGC upregulation in response to bFGF in gastric cancer might be implicated in carcinogenesis through dysregulation of growth modulator [1].
The FIGC gene was found to encode a polypeptide of 381 amino acids with a novel RING finger module at the NH2-terminus and the COOH-terminal proline-rich region [1].

References

FIGC, a novel FGF-induced ubiquitin-protein ligase in gastric cancers. Jang, J.H. FEBS Lett. (2004) [Pubmed]
Suppression of KCMF1 by constitutive high CD99 expression is involved in the migratory ability of Ewing's sarcoma cells. Kreppel, M., Aryee, D.N., Schaefer, K.L., Amann, G., Kofler, R., Poremba, C., Kovar, H. Oncogene (2006) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

AgaP_AGAP002670	Anopheles gambiae str. PEST
KCMF1	Bos taurus
LOC475773	Canis lupus familiaris
kcmf1	Danio rerio
KCMF1	Gallus gallus
KCMF1	Macaca mulatta
Kcmf1	Mus musculus
KCMF1	Pan troglodytes
Kcmf1	Rattus norvegicus

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