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Gene Review:

GYS1 - glycogen synthase 1 (muscle)

Sus scrofa

Zuo, B. et al., Fontanesi, L. et al., te Pas, M.F. et al.

Fontanesi, Davoli, Nanni Costa, Scotti, Russo, te Pas, Leenhouwers, Knol, Booij, Priem, van der Lende,

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High impact information on GYS1

Polymorphism, linkage mapping and expression pattern of the porcine skeletal muscle glycogen synthase (GYS1) gene [1].
The reverse transcriptase-polymerase chain reaction revealed that the porcine GYS1 gene was expressed in spleen, lung, liver, kidney, small intestine, skeletal muscle, heart and stomach, with the highest expression in skeletal muscle [1].
In this study, a G/A single nucleotide polymorphism in GYS1 intron 7 detected as a FokI PCR-restriction fragment length polymorphism (PCR-RFLP) showed allele frequency differences among five Chinese indigenous pig breeds and three western commercial pig breeds [1].
Marker polymorphisms in the porcine genes for muscle glycogen synthase (GYS1) and muscle glycogen phosphorylase (PYGM) [2].
Physical mapping, obtained by somatic cell hybrid panel analysis, confirmed the linkage assignments of PRKAB1 and GAA and localized ALDOA, PRKAB2 and GYS1 to SSC3, SSC4 and SSC6, respectively [3].

References

Polymorphism, linkage mapping and expression pattern of the porcine skeletal muscle glycogen synthase (GYS1) gene. Zuo, B., Xiong, Y.Z., Deng, C.Y., Su, Y.H., Wang, J., Lei, M.G., Li, F.E., Jiang, S.W., Zheng, R. Anim. Genet. (2005) [Pubmed]
Marker polymorphisms in the porcine genes for muscle glycogen synthase (GYS1) and muscle glycogen phosphorylase (PYGM). te Pas, M.F., Leenhouwers, J.I., Knol, E.F., Booij, M., Priem, J., van der Lende, T. Anim. Genet. (2003) [Pubmed]
Study of candidate genes for glycolytic potential of porcine skeletal muscle: identification and analysis of mutations, linkage and physical mapping and association with meat quality traits in pigs. Fontanesi, L., Davoli, R., Nanni Costa, L., Scotti, E., Russo, V. Cytogenet. Genome Res. (2003) [Pubmed]

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