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Gene Review

Fut4  -  fucosyltransferase 4 (alpha (1,3)...

Rattus norvegicus

Synonyms: Alpha-(1,3)-fucosyltransferase 4, Fuc-TIV, FucT-IV, Fucosyltransferase 4, Fucosyltransferase IV, ...
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High impact information on Fut4

  • Infection of cerebellar astrocytes with viral vectors expressing either Fuc-TIV, or Fuc-TIX, caused dramatic increases in CD15 expression in the presence of continued endogenous SGC epitope expression [1].
  • Comparison of the rFuc-T predicted amino acid sequence with those of previously cloned human and murine fucosyltransferases showed highest degree of homology to murine Fuc-TIV (87% identity) and human Fuc-TIV (78% identity), with lower homology (41-49% identity) to Fuc-TIII, V, VI, and VII [2].


  1. Viral vector-mediated delivery of competing glycosyltransferases modifies epitope expression cell specifically. Baboval, T., Liang, S., Smith, F.I. J. Neurosci. Res. (2002) [Pubmed]
  2. Cloning of a rat alpha1,3-fucosyltransferase gene: a member of the fucosyltransferase IV family. Sajdel-Sulkowska, E.M., Smith, F.I., Wiederschain, G., McCluer, R.H. Glycoconj. J. (1997) [Pubmed]
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