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Gene Review

PKD1  -  polycystic kidney disease 1 (autosomal...

Canis lupus familiaris

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Disease relevance of PKD1


High impact information on PKD1

  • Intron 21 of dog PKD1 lacked the polypyrimidine tract characteristic of the human gene, whereas pyrimidine-rich elements were identified in canine intron 30 [2].


  1. No disease-associated mutations found in the coding sequence of the canine polycystic kidney disease gene 1 in Bull Terriers with polycystic kidney disease. O'Leary, C.A., Atwell, R.B., Laing, N.G. Anim. Genet. (2003) [Pubmed]
  2. Canine PKD1 is a single-copy gene: genomic organization and comparative analysis. Dackowski, W.R., Luderer, H.F., Manavalan, P., Bukanov, N.O., Russo, R.J., Roberts, B.L., Klinger, K.W., Ibraghimov-Beskrovnaya, O. Genomics (2002) [Pubmed]
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