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Gene Review:

LTB4R - leukotriene B4 receptor

Bos taurus

Igarashi, T. et al., Koyama, S. et al.

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High impact information on LTB4R

Characterization of the leukotriene B4 receptor in porcine leukocytes. Separation and reconstitution with heterotrimeric GTP-binding proteins [1].
When cDNAs for LTB4 receptor (BLT) were cloned it was found that they belong to a guanine nucleotide-binding regulatory protein (G-protein)-coupled receptor superfamily [1].
The lowest peak, which represented the predominant activity, was blocked by leukotriene B4-receptor antagonist (P < 0. 01) but not by platelet-activating factor-receptor antagonist [2].

References

Characterization of the leukotriene B4 receptor in porcine leukocytes. Separation and reconstitution with heterotrimeric GTP-binding proteins. Igarashi, T., Yokomizo, T., Tsutsumi, O., Taketani, Y., Shimizu, T., Izumi, T. Eur. J. Biochem. (1999) [Pubmed]
Acetylcholine and substance P stimulate bronchial epithelial cells to release eosinophil chemotactic activity. Koyama, S., Sato, E., Nomura, H., Kubo, K., Nagai, S., Izumi, T. J. Appl. Physiol. (1998) [Pubmed]

Contributions to this collaborative article are from individual authors of WikiGenes or mined by the WikiGenes Data Mining Engine from MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.About WikiGenes Open Access Licence Privacy Policy Terms of Use apsburg

LOC100329657	Danio rerio
si:ch211-272h9.2	Danio rerio
LTB4R	Homo sapiens
LTB4R	Macaca mulatta
Ltb4r1	Mus musculus
LTB4R	Pan troglodytes
Ltb4r	Rattus norvegicus
ltb4r	Xenopus (Silurana) tropicalis

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