The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
Gene Review

D4Mit278  -  DNA segment, Chr 4, Massachusetts...

Mus musculus

Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of D4Mit278

  • In male NZO x F1 backcross mice, a major susceptibility locus for the development of hyperglycemia and hypoinsulinemia (Nidd/SJL) was identified on chromosome 4 between the markers D4Mit278 and D4Mit232, 10-28 cM distal of the previously described Nidd1 locus [1].

High impact information on D4Mit278

  • The rct locus essential for the onset of the cataract was tightly linked to D4Mit278 on Chromosome (Chr) 4 with no recombination [2].


  1. Type 2 diabetes-like hyperglycemia in a backcross model of NZO and SJL mice: characterization of a susceptibility locus on chromosome 4 and its relation with obesity. Plum, L., Kluge, R., Giesen, K., Altmüller, J., Ortlepp, J.R., Joost, H.G. Diabetes (2000) [Pubmed]
  2. Two interactive genes responsible for a new inherited cataract (RCT) in the mouse. Maeda, Y.Y., Funata, N., Takahama, S., Sugata, Y., Yonekawa, H. Mamm. Genome (2001) [Pubmed]
WikiGenes - Universities