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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

ELMO2  -  engulfment and cell motility 2

Homo sapiens

Synonyms: CED-12, CED12, CED12A, ELMO-2, Engulfment and cell motility protein 2, ...
 
 
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High impact information on ELMO2

  • Here, we describe an additional member of this signaling pathway, ced-12, and its mammalian homologs, elmo1 and elmo2 [1].
  • The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway [2].

References

  1. CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration. Gumienny, T.L., Brugnera, E., Tosello-Trampont, A.C., Kinchen, J.M., Haney, L.B., Nishiwaki, K., Walk, S.F., Nemergut, M.E., Macara, I.G., Francis, R., Schedl, T., Qin, Y., Van Aelst, L., Hengartner, M.O., Ravichandran, K.S. Cell (2001) [Pubmed]
  2. The C. elegans PH domain protein CED-12 regulates cytoskeletal reorganization via a Rho/Rac GTPase signaling pathway. Zhou, Z., Caron, E., Hartwieg, E., Hall, A., Horvitz, H.R. Dev. Cell (2001) [Pubmed]
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