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Gene Review

Tmem57  -  transmembrane protein 57

Mus musculus

Synonyms: 1110007C24Rik, 9230118A01Rik, AI317300, AI606104, Brain-specific adapter protein C61, ...
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High impact information on Tmem57

  • Substitution of both C61 and C69 present in region C, caused almost 90% loss of activity that could be partially overcome by transfecting more expression plasmid [1].
  • From E14.5 to birth, C61 was highly expressed in all neuronal differentiation fields, with the highest signal in the telencephalic cortical plate and mitral cells in the olfactory bulb [2].


  1. A truncated mutant (residues 58-140) of the hepatitis B virus X protein retains transactivation function. Kumar, V., Jayasuryan, N., Kumar, R. Proc. Natl. Acad. Sci. U.S.A. (1996) [Pubmed]
  2. Identification of a novel brain-specific and Reelin-regulated gene that encodes a protein colocalized with synapsin. Kuvbachieva, A., Bestel, A.M., Tissir, F., Maloum, I., Guimiot, F., Ramoz, N., Bourgeois, F., Moalic, J.M., Goffinet, A.M., Simonneau, M. Eur. J. Neurosci. (2004) [Pubmed]
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