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Gene Review

Dmap1  -  DNA methyltransferase 1-associated protein 1

Mus musculus

Synonyms: 1500016M21Rik, DNMAP1, DNMT1-associated protein 1, DNMTAP1, Dmtap1, ...
 
 
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Disease relevance of Dmap1

 

High impact information on Dmap1

  • Of five vaccine formulations based on well-established monocationic lipids in the form of unsized liposomes, three (DC-Chol, DDAB, and DSTAP-based) resulted in low serum and local responses, while two others (DMTAP and DOTAP-based vaccines) induced both systemic and local vigorous Th1+Th2 immune responses [2].

References

  1. Toxicity and immunomodulatory activity of liposomal vectors formulated with cationic lipids toward immune effector cells. Filion, M.C., Phillips, N.C. Biochim. Biophys. Acta (1997) [Pubmed]
  2. A new intranasal influenza vaccine based on a novel polycationic lipid-ceramide carbamoyl-spermine (CCS) I. Immunogenicity and efficacy studies in mice. Joseph, A., Itskovitz-Cooper, N., Samira, S., Flasterstein, O., Eliyahu, H., Simberg, D., Goldwaser, I., Barenholz, Y., Kedar, E. Vaccine (2006) [Pubmed]
 
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