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Gene Review

FCAR  -  Fc fragment of IgA, receptor for

Macaca mulatta

 
 
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High impact information on FCAR

  • The human FcalphaR, CD89, was the first IgA Fc receptor to be identified and binding of IgA-coated particles to CD89 triggers numerous cellular effector functions, including phagocytosis, antibody-dependent cellular cytotoxicity, and release of inflammatory mediators, all of which may play an important role in both systemic and mucosal immunity [1].

References

  1. Cloning and characterization of equine CD89 and identification of the CD89 gene in chimpanzees and rhesus macaques. Morton, H.C., Pleass, R.J., Storset, A.K., Brandtzaeg, P., Woof, J.M. Immunology (2005) [Pubmed]
 
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