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Gene Review

MED22  -  mediator complex subunit 22

Homo sapiens

Synonyms: MED24, Med24, Mediator complex subunit 22, Mediator of RNA polymerase II transcription subunit 22, SURF5, ...
 
 
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Disease relevance of SURF5

  • Clinical scores of erythema and determination of the MED 24 h after irradiation did not show statistically significant changes between the exposed areas before and after bexarotene treatment or between the two doses tested [1].
  • CONCLUSION: Individuals who surf 5 years or less are unlikely to develop exostoses unless they are surfing greater than 50 sessions per year [2].

References

  1. Effects of oral bexarotene (targretin) on the minimal erythema dose for broadspectrum UVB light. Smit, J.V., De Jong, E.M., Van De Kerkhof, P.C. Skin Pharmacol. Appl. Skin Physiol. (2003) [Pubmed]
  2. Exostoses of the external auditory canal in Oregon surfers. Deleyiannis, F.W., Cockcroft, B.D., Pinczower, E.F. American journal of otolaryngology. (1996) [Pubmed]
 
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