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Gene Review:

Speer1-ps1 - spermatogenesis associated glutamate (E)...

Mus musculus

Synonyms: 4921519H07Rik, SPEER-1, Speer1-ps

Spiess, A.N. et al.

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High impact information on Speer1-ps1

Three members were chosen for more detailed characterization: SPEER-1 (pseudogene), SPEER-2, and SPEER-4D [1].
Because of this property, the family has been named SPErm-associated glutamate (E)-Rich protein (SPEER) [1].
While there are no true homologies to other proteins in the genome databases, some motifs are present that suggest a relationship to nuclear matrix proteins, implying that the SPEER family is a new group of haploid sperm-specific nuclear factors [1].
An antibody raised against a peptide region of SPEER-4D, which probably cross-reacts with other SPEER members, immunohistochemically stains the nuclei of early round spermatids [1].

References

SPEER--a new family of testis-specific genes from the mouse. Spiess, A.N., Walther, N., Müller, N., Balvers, M., Hansis, C., Ivell, R. Biol. Reprod. (2003) [Pubmed]

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