Gene Review:
TUBG1 - tubulin, gamma 1
Homo sapiens
Synonyms:
CDCBM4, GCP-1, Gamma-1-tubulin, Gamma-tubulin complex component 1, TUBG, ...
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High impact information on TUBG1
- We now report the identification of a second expressed human gamma-tubulin gene (TUBG2) and a gamma-tubulin pseudogene (TUBG1P) in addition to the previously identified gamma-tubulin gene (TUBG1) [1].
- Previous studies of gamma-tubulin in human tissues and cell lines have been based on the tacit assumption that a single gamma-tubulin (the gamma-tubulin encoded by TUBG1) was present [1].
Other interactions of TUBG1
- The proteins encoded by TUBG1 and TUBG2 share 97.3% amino acid identity, and the two genes are coexpressed in a variety of tissues [1].
Analytical, diagnostic and therapeutic context of TUBG1
- While this assumption is not correct, the similarity of the products of TUBG1 and TUBG2 suggests that results of previous immunolocalization and immunoprecipitation studies in human cells and tissues are likely to be valid [1].
References
- The gamma-tubulin gene family in humans. Wise, D.O., Krahe, R., Oakley, B.R. Genomics (2000) [Pubmed]
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