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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

TBC1D3  -  TBC1 domain family, member 3

Homo sapiens

Synonyms: DKFZp434P2235, PRC17, Prostate cancer gene 17 protein, Protein TRE17-alpha, Rab GTPase-activating protein PRC17, ...
 
 
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Regulatory relationships of TBC1D3

  • TBC1D3 suppresses polyubiquitination of the EGFR and the recruitment of c-Cbl [1].

References

  1. The hominoid-specific oncogene TBC1D3 activates Ras and modulates epidermal growth factor receptor signaling and trafficking. Wainszelbaum, M.J., Charron, A.J., Kong, C., Kirkpatrick, D.S., Srikanth, P., Barbieri, M.A., Gygi, S.P., Stahl, P.D. J. Biol. Chem. (2008) [Pubmed]
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