The world's first wiki where authorship really matters (Nature Genetics, 2008). Due credit and reputation for authors. Imagine a global collaborative knowledge base for original thoughts. Search thousands of articles and collaborate with scientists around the globe.

wikigene or wiki gene protein drug chemical gene disease author authorship tracking collaborative publishing evolutionary knowledge reputation system wiki2.0 global collaboration genes proteins drugs chemicals diseases compound
Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)



Gene Review

SLMAP  -  sarcolemma associated protein

Homo sapiens

Synonyms: KIAA1601, SLAP, Sarcolemmal membrane-associated protein, Sarcolemmal-associated protein, UNQ1847/PRO3577
Welcome! If you are familiar with the subject of this article, you can contribute to this open access knowledge base by deleting incorrect information, restructuring or completely rewriting any text. Read more.

Disease relevance of SLMAP


High impact information on SLMAP

  • These data provide further evidence that dystrophin is a sarcolemma-associated protein, that it is developmentally regulated, and that it is absent or greatly reduced in quantity in skeletal muscle cultures from patients with DMD [2].
  • In conclusion, in normal human muscle cultures DGC and vinculin-talin-integrin proteins are first localized in the perinuclear region, then they diffuse in the cytoplasm and finally form at the plasma membrane into typical rib-like structures that are sarcolemma-associated [3].
  • This reciprocal control may determine, in different conditions, the prevalence of one system over another with a consequent transmission of different messages to the sarcolemma-associated cytoskeleton [4].


  1. Adolescents with muscular dystrophies. Papazian, O., Alfonso, I. Adolescent medicine (Philadelphia, Pa.) (2002) [Pubmed]
  2. Immunocytochemical study of dystrophin in muscle cultures from patients with Duchenne muscular dystrophy and unaffected control patients. Miranda, A.F., Bonilla, E., Martucci, G., Moraes, C.T., Hays, A.P., Dimauro, S. Am. J. Pathol. (1988) [Pubmed]
  3. Culture of human skeletal muscle myoblasts: timing appearance and localization of dystrophin-glycoprotein complex and vinculin-talin-integrin complex. Trimarchi, F., Favaloro, A., Fulle, S., Magaudda, L., Puglielli, C., Di Mauro, D. Cells Tissues Organs (Print) (2006) [Pubmed]
  4. Distribution and localization of vinculin-talin-integrin system and dystrophin-glycoprotein complex in human skeletal muscle. Immunohistochemical study using confocal laser scanning microscopy. Anastasi, G., Amato, A., Tarone, G., Vita, G., Monici, M.C., Magaudda, L., Brancaccio, M., Sidoti, A., Trimarchi, F., Favaloro, A., Cutroneo, G. Cells Tissues Organs (Print) (2003) [Pubmed]
WikiGenes - Universities