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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

DCTPP1  -  dCTP pyrophosphatase 1

Homo sapiens

Synonyms: CDA03, Deoxycytidine-triphosphatase 1, MGC5627, RS21C6, XTP3-transactivated gene A protein, ...
 
 
 
 
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Disease relevance of XTP3TPA

  • Structure-guided analysis of the new dimeric dUTPase family revealed its sequence relationship to the phage T4 dCTPase, phosphoribosyl-ATP pyrophosphatase HisE, NTP pyrophosphatase MazG, and several uncharacterized protein families, including the human protein XTP3TPA (RS21-C6), which is overexpressed in embryonic and cancer cells [1].

References

  1. Dimeric dUTPases, HisE, and MazG belong to a new superfamily of all-alpha NTP pyrophosphohydrolases with potential "house-cleaning" functions. Moroz, O.V., Murzin, A.G., Makarova, K.S., Koonin, E.V., Wilson, K.S., Galperin, M.Y. J. Mol. Biol. (2005) [Pubmed]
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