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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

PANK3  -  pantothenate kinase 3

Homo sapiens

Synonyms: FLJ12899, Pantothenate kinase 3, Pantothenic acid kinase 3, hPanK3
 
 
 
 
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Disease relevance of PANK3

  • Bezafibrate (BF), a hypolipidemic drug and a peroxisome proliferator activator receptor-alpha (PPARalpha) agonist, specifically increased hPANK1alpha mRNA expression in human hepatoblastoma (HepG2) cells as a function of time and dose of the drug, compared with hPANK1beta, hPANK2, and hPANK3, which did not significantly increase [1].

References

  1. PPARalpha controls the intracellular coenzyme A concentration via regulation of PANK1alpha gene expression. Ramaswamy, G., Karim, M.A., Murti, K.G., Jackowski, S. J. Lipid Res. (2004) [Pubmed]
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