Gene Review:
PALB2 - partner and localizer of BRCA2
Homo sapiens
Synonyms:
FANCN, FLJ21816, PNCA3, Partner and localizer of BRCA2
- The breast cancer susceptibility mutation PALB2 1592delT is associated with an aggressive tumor phenotype. Heikkinen, T., Kärkkäinen, H., Aaltonen, K., Milne, R.L., Heikkilä, P., Aittomäki, K., Blomqvist, C., Nevanlinna, H. Clin. Cancer Res. (2009)
- MRG15 is a novel PALB2-interacting factor involved in homologous recombination. Sy, S.M., Huen, M.S., Chen, J. J. Biol. Chem. (2009)
- Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination. Buisson, R., Dion-Côté, A.M., Coulombe, Y., Launay, H., Cai, H., Stasiak, A.Z., Stasiak, A., Xia, B., Masson, J.Y. Nat. Struct. Mol. Biol. (2010)
- Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Dray, E., Etchin, J., Wiese, C., Saro, D., Williams, G.J., Hammel, M., Yu, X., Galkin, V.E., Liu, D., Tsai, M.S., Sy, S.M., Schild, D., Egelman, E., Chen, J., Sung, P. Nat. Struct. Mol. Biol. (2010)