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Gene Review

LBH  -  limb bud and heart development

Homo sapiens

Synonyms: Protein LBH, hLBH
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High impact information on LBH

  • Our findings implicate LBH as a candidate gene for CHD associated with partial trisomy 2p syndrome and suggest an important role of Lbh in transcriptional control during normal cardiogenesis [1].
  • Their mean values during characteristic hiking positions (sitting - S, upright hiking - UH, leaning backwards hiking - LBH) were compared by means of repeated ANOVA measures [2].

Biological context of LBH

  • Here we show that human LBH maps to chromosome 2p23, a genomic region related to CHD in partial trisomy 2p syndrome [1].


  1. Congenital heart disease reminiscent of partial trisomy 2p syndrome in mice transgenic for the transcription factor Lbh. Briegel, K.J., Baldwin, H.S., Epstein, J.A., Joyner, A.L. Development (2005) [Pubmed]
  2. EMG analysis of muscle load during simulation of characteristic postures in dinghy sailing. Sekulic, D., Medved, V., Rausavljevi, N., Medved, V. The Journal of sports medicine and physical fitness. (2006) [Pubmed]
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