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Gene Review

NUAK2  -  NUAK family, SNF1-like kinase, 2

Homo sapiens

Synonyms: FLJ90349, NUAK family SNF1-like kinase 2, OMPHK2, Omphalocele kinase 2, SNARK, ...
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High impact information on NUAK2

  • The Snark is a Boojum: the continuing problem of drug resistance in the antiangiogenic era [1].
  • A BLAST search analysis using rat SNARK protein yielded a single high homology clone, DKFZp434J037, isolated from human testis, and since its hypothetical protein showed 84% homology to rat SNARK protein, we assumed DKFZp434J037 to be the human SNARK cDNA [2].


  1. The Snark is a Boojum: the continuing problem of drug resistance in the antiangiogenic era. Miller, K.D., Sweeney, C.J., Sledge, G.W. Ann. Oncol. (2003) [Pubmed]
  2. Induction of cell-cell detachment during glucose starvation through F-actin conversion by SNARK, the fourth member of the AMP-activated protein kinase catalytic subunit family. Suzuki, A., Kusakai, G., Kishimoto, A., Minegichi, Y., Ogura, T., Esumi, H. Biochem. Biophys. Res. Commun. (2003) [Pubmed]
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