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Hoffmann, R. A wiki for the life sciences where authorship matters. Nature Genetics (2008)
 

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Gene Review: 

Serpina7  -  serpin peptidase inhibitor, clade A (alpha...

Rattus norvegicus

Synonyms: Serpin A7, T4-binding globulin, Tbg, Thyroxine-binding globulin
 
 
 
 
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High impact information on Serpina7

  • The non-iodine containing compound 8-anilino-1-naphthalene sulphonic acid (ANS) appeared to be a very strong competitive inhibitor of both 5'-deiodinations (Ki 4.3-4.7 microM), whereas salicylic acid, which as ANS inhibits the binding of iodothyronines to T4-binding globulin, inhibited these reactions to a much lesser extent (Ki 300-500 microM) [1].

References

  1. One enzyme for the 5'-deiodination of 3,3',5'-triiodothyronine and 3',5'-diiodothyronine in rat liver. Fekkes, D., Hennemann, G., Visser, T.J. Biochem. Pharmacol. (1982) [Pubmed]
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