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Gene Review

FLD  -  lysine-specific histone demethylase 1...

Arabidopsis thaliana

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High impact information on FLD

  • Several of the identified components (FY, FVE, and FLD) are homologous to yeast and mammalian proteins with rather generic roles in gene regulation [1].
  • The additive phenotype observed in double mutants provides evidence to support that these two genes, FLD and CO, are not only involved in rosette-to-inflorescence transition but also involved in the flower formation [2].
  • Other components of the autonomous pathway, FVE and FLD, regulate FLC epigenetically [3].


  1. Additional targets of the Arabidopsis autonomous pathway members, FCA and FY. Marquardt, S., Boss, P., Hadfield, J., Dean, C. J. Exp. Bot. (2006) [Pubmed]
  2. FLD interacts with CO to affect both flowering time and floral initiation in Arabidopsis thaliana. Yang, C.H., Chou, M.L. Plant Cell Physiol. (1999) [Pubmed]
  3. RNA processing and Arabidopsis flowering time control. Simpson, G.G., Quesada, V., Henderson, I.R., Dijkwel, P.P., Macknight, R., Dean, C. Biochem. Soc. Trans. (2004) [Pubmed]
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