Gene Review:
FLC - MADS-box protein FLOWERING LOCUS C
Arabidopsis thaliana
Synonyms:
AGAMOUS-like 25, AGL25, FLF, FLOWERING LOCUS C, FLOWERING LOCUS F, ...
- The PHYTOCHROME C photoreceptor gene mediates natural variation in flowering and growth responses of Arabidopsis thaliana. Balasubramanian, S., Sureshkumar, S., Agrawal, M., Michael, T.P., Wessinger, C., Maloof, J.N., Clark, R., Warthmann, N., Chory, J., Weigel, D. Nat. Genet. (2006)
- Epigenetic maintenance of the vernalized state in Arabidopsis thaliana requires LIKE HETEROCHROMATIN PROTEIN 1. Sung, S., He, Y., Eshoo, T.W., Tamada, Y., Johnson, L., Nakahigashi, K., Goto, K., Jacobsen, S.E., Amasino, R.M. Nat. Genet. (2006)
- Regulation of flowering time by FVE, a retinoblastoma-associated protein. Ausín, I., Alonso-Blanco, C., Jarillo, J.A., Ruiz-García, L., Martínez-Zapater, J.M. Nat. Genet. (2004)
- Prevention of early flowering by expression of FLOWERING LOCUS C requires methylation of histone H3 K36. Zhao, Z., Yu, Y., Meyer, D., Wu, C., Shen, W.H. Nat. Cell Biol. (2005)
- SUPPRESSOR OF FRI 4 encodes a nuclear-localized protein that is required for delayed flowering in winter-annual Arabidopsis. Kim, S.Y., Michaels, S.D. Development (2006)
- Nonadditive regulation of FRI and FLC loci mediates flowering-time variation in Arabidopsis allopolyploids. Wang, J., Tian, L., Lee, H.S., Chen, Z.J. Genetics (2006)
- SUPPRESSOR OF FRIGIDA4, Encoding a C2H2-Type Zinc Finger Protein, Represses Flowering by Transcriptional Activation of Arabidopsis FLOWERING LOCUS C. Kim, S., Choi, K., Park, C., Hwang, H.J., Lee, I. Plant Cell (2006)
- The PHD Finger Protein VRN5 Functions in the Epigenetic Silencing of Arabidopsis FLC. Greb, T., Mylne, J.S., Crevillen, P., Geraldo, N., An, H., Gendall, A.R., Dean, C. Curr. Biol. (2007)
- Establishment of the vernalization-responsive, winter-annual habit in Arabidopsis requires a putative histone H3 methyl transferase. Kim, S.Y., He, Y., Jacob, Y., Noh, Y.S., Michaels, S., Amasino, R. Plant Cell (2005)
- ARABIDOPSIS TRITHORAX1 dynamically regulates FLOWERING LOCUS C activation via histone 3 lysine 4 trimethylation. Pien, S., Fleury, D., Mylne, J.S., Crevillen, P., Inzé, D., Avramova, Z., Dean, C., Grossniklaus, U. Plant. Cell (2008)
- The VERNALIZATION INDEPENDENCE 4 gene encodes a novel regulator of FLOWERING LOCUS C. Zhang, H., van Nocker, S. Plant J. (2002)
- Antagonistic regulation of flowering-time gene SOC1 by CONSTANS and FLC via separate promoter motifs. Hepworth, S.R., Valverde, F., Ravenscroft, D., Mouradov, A., Coupland, G. EMBO J. (2002)
- A new Arabidopsis gene, FLK, encodes an RNA binding protein with K homology motifs and regulates flowering time via FLOWERING LOCUS C. Lim, M.H., Kim, J., Kim, Y.S., Chung, K.S., Seo, Y.H., Lee, I., Kim, J., Hong, C.B., Kim, H.J., Park, C.M. Plant Cell (2004)
- LHP1, the Arabidopsis homologue of HETEROCHROMATIN PROTEIN1, is required for epigenetic silencing of FLC. Mylne, J.S., Barrett, L., Tessadori, F., Mesnage, S., Johnson, L., Bernatavichute, Y.V., Jacobsen, S.E., Fransz, P., Dean, C. Proc. Natl. Acad. Sci. U.S.A. (2006)
- Additional targets of the Arabidopsis autonomous pathway members, FCA and FY. Marquardt, S., Boss, P., Hadfield, J., Dean, C. J. Exp. Bot. (2006)
- Polycomb-group proteins repress the floral activator AGL19 in the FLC-independent vernalization pathway. Schönrock, N., Bouveret, R., Leroy, O., Borghi, L., Köhler, C., Gruissem, W., Hennig, L. Genes Dev. (2006)
- Loss of FLOWERING LOCUS C activity eliminates the late-flowering phenotype of FRIGIDA and autonomous pathway mutations but not responsiveness to vernalization. Michaels, S.D., Amasino, R.M. Plant Cell (2001)
- The Arabidopsis RNA-binding protein FCA requires a lysine-specific demethylase 1 homolog to downregulate FLC. Liu, F., Quesada, V., Crevillén, P., Bäurle, I., Swiezewski, S., Dean, C. Mol. Cell (2007)
- Establishment of the winter-annual growth habit via FRIGIDA-mediated histone methylation at FLOWERING LOCUS C in Arabidopsis. Jiang, D., Gu, X., He, Y. Plant. Cell (2009)
- Attenuation of FLOWERING LOCUS C activity as a mechanism for the evolution of summer-annual flowering behavior in Arabidopsis. Michaels, S.D., He, Y., Scortecci, K.C., Amasino, R.M. Proc. Natl. Acad. Sci. U.S.A. (2003)
- EARLY IN SHORT DAYS 1 (ESD1) encodes ACTIN-RELATED PROTEIN 6 (AtARP6), a putative component of chromatin remodelling complexes that positively regulates FLC accumulation in Arabidopsis. Martin-Trillo, M., Lázaro, A., Poethig, R.S., Gómez-Mena, C., Piñeiro, M.A., Martinez-Zapater, J.M., Jarillo, J.A. Development (2006)
- Cloning, characterization and genetic engineering of FLC homolog in Thellungiella halophila. Fang, Q., Xu, Z., Song, R. Biochem. Biophys. Res. Commun. (2006)