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Gene Review

MRP3  -  ABC transporter C family member 3

Arabidopsis thaliana

Synonyms: ABCC3, ATMRP3, ATP-binding cassette C3, MJG19.26, MJG19_26, ...
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High impact information on ATMRP3

  • The kinetic properties of the A. thaliana MRP-like protein (AtMRP3) are very similar to those previously described for the vacuolar glutathione-conjugate transporter of barley and mung bean [1].
  • The related transporters MRP2 and MRP3 have overlapping substrate specificities with MRP1 but different tissue distributions, and evidence that they also have chemoprotective functions are discussed [2].


  1. An ABC-transporter of Arabidopsis thaliana has both glutathione-conjugate and chlorophyll catabolite transport activity. Tommasini, R., Vogt, E., Fromenteau, M., Hörtensteiner, S., Matile, P., Amrhein, N., Martinoia, E. Plant J. (1998) [Pubmed]
  2. Toxicological relevance of the multidrug resistance protein 1, MRP1 (ABCC1) and related transporters. Leslie, E.M., Deeley, R.G., Cole, S.P. Toxicology (2001) [Pubmed]
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